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Essentially, L-DOPA is transported across the blood brain barrier by LAT-1 (L or Large amino acid transporter). This transporter moves amino acids like phenylalanine and tyrosine across the blood brain barrier. Without a transporter, a molecule needs to be lipid soluble to cross the blood brain barrier.
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Use Sinemet Cr exactly as prescribed by your doctor. Do not take more of this drug than is recommended. Take this medication with a full glass of water with or without food at the same time every day. Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Essentially, L-DOPA is transported across the blood brain barrier by LAT-1 (L or Large amino acid transporter). This transporter moves amino acids like phenylalanine and tyrosine across the blood brain barrier. Without a transporter, a molecule needs to be lipid soluble to cross the blood brain barrier.
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